Perfluorohexyloctane
Dry eye · Rx
Trade namesMiebo
Drug classAnti-evaporative ocular surface agent
Strength100%
AvailabilityRx
Mechanism of actionSemifluorinated alkane that forms a monolayer at the air-tear interface, markedly reducing tear evaporation. Water- and preservative-free.
Indication / reason for useSigns and symptoms of dry eye disease, particularly evaporative DED / MGD.
Usual adult dosing1 drop in each eye 4×/day.
PreservativePreservative-free (water-free) , a preservative-free option exists
Contact lensesManufacturer advises removing contact lenses before use.
Common / important adverse effectsBlurred vision, eye redness.
Contraindications & cautionsNone specific; no known drug interactions.
Pregnancy / lactationNo human data; negligible systemic exposure expected.
Practice notesVery low drop volume; spreads rapidly, a single drop is sufficient.
Chair-side reference only. Dosing, contraindications and pregnancy guidance here are not exhaustive. Confirm against the current prescribing information and the patient’s full history before prescribing or advising.