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Fluorometholone

Anti-inflammatory · Rx
Trade namesFML 0.1%, FML Forte 0.25%, Flarex (FML acetate 0.1%)
Drug classCorticosteroid, fluorinated (suspension)
Strength0.1%, 0.25%
AvailabilityRx
Mechanism of actionFluorinated corticosteroid with relatively poor corneal penetration, modest anti-inflammatory potency, lower IOP effect than prednisolone.
Indication / reason for useMilder anterior segment / ocular surface inflammation, allergic keratoconjunctivitis, episcleritis, phlyctenular disease; useful in children and steroid responders.
Usual adult dosing1-2 drops 2-4×/day; shake well.
PreservativeBAK 0.004%
Contact lensesAvoid lens wear during active inflammation.
Common / important adverse effectsLower but real IOP-rise risk with prolonged use; cataract, infection potentiation.
Contraindications & cautionsEpithelial herpes simplex keratitis, other active viral/fungal/mycobacterial infection.
Pregnancy / lactationLimited data.
Practice notesWeaker than prednisolone, not adequate for significant uveitis.
Chair-side reference only. Dosing, contraindications and pregnancy guidance here are not exhaustive. Confirm against the current prescribing information and the patient’s full history before prescribing or advising.

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