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Erythromycin

Anti-infective · Rx
Trade namesIlotycin, Romycin
Drug classAntibiotic, macrolide (ointment)
Strength0.5% ophthalmic ointment
AvailabilityRx
Mechanism of actionBinds the 50S ribosomal subunit; bacteriostatic; Gram-positive and some atypical (Chlamydia) coverage.
Indication / reason for useBacterial conjunctivitis and blepharitis; neonatal ocular prophylaxis (gonococcal/chlamydial); lubricating antibacterial cover for abrasions and exposure.
Usual adult dosingRibbon into the lower fornix up to 6×/day (acute) or at bedtime (blepharitis).
PreservativePreservative-free ointment base , a preservative-free option exists
Contact lensesDo not wear lenses while treating an ocular infection.
Common / important adverse effectsTransient blur, mild irritation, rare hypersensitivity.
Contraindications & cautionsMacrolide hypersensitivity.
Pregnancy / lactationConsidered low risk; commonly used.
Practice notesWell tolerated for lid disease; the ointment vehicle itself soothes.
Chair-side reference only. Dosing, contraindications and pregnancy guidance here are not exhaustive. Confirm against the current prescribing information and the patient’s full history before prescribing or advising.

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