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Cromolyn sodium

Allergy · Rx
Trade namesCrolom, Opticrom
Drug classMast-cell stabilizer
Strength4%
AvailabilityRx
Mechanism of actionInhibits mast-cell degranulation; prophylactic, no intrinsic antihistamine effect.
Indication / reason for useVernal keratoconjunctivitis, giant papillary conjunctivitis, allergic keratoconjunctivitis.
Usual adult dosing1-2 drops in each eye 4-6×/day at regular intervals.
PreservativeBAK 0.01%
Contact lensesDo not wear lenses during treatment of significant allergic eye disease.
Common / important adverse effectsTransient stinging on instillation.
Contraindications & cautionsHypersensitivity.
Pregnancy / lactationLong track record; considered low risk.
Practice notesNeeds several days of regular use before full effect, not a rescue drop.
Chair-side reference only. Dosing, contraindications and pregnancy guidance here are not exhaustive. Confirm against the current prescribing information and the patient’s full history before prescribing or advising.

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