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Azelastine

Allergy · Rx
Trade namesOptivar
Drug classAntihistamine + mast-cell stabilizer (dual-acting)
Strength0.05%
AvailabilityRx
Mechanism of actionH1-antagonist; mast-cell stabilization and reduced expression of ICAM-1 on epithelium.
Indication / reason for useItching associated with allergic conjunctivitis.
Usual adult dosing1 drop in each eye twice daily.
PreservativeBAK 0.0125%
Contact lensesRemove lenses; reinsert after 10 min.
Common / important adverse effectsBitter taste (common), transient stinging, headache.
Contraindications & cautionsHypersensitivity.
Pregnancy / lactationLimited data.
Chair-side reference only. Dosing, contraindications and pregnancy guidance here are not exhaustive. Confirm against the current prescribing information and the patient’s full history before prescribing or advising.

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