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Alcaftadine

Allergy · OTC
Trade namesLastacaft
Drug classAntihistamine + mast-cell stabilizer (dual-acting)
Strength0.25%
AvailabilityOTC
Mechanism of actionH1/H2/H4-receptor antagonist with mast-cell stabilization; also reduces eosinophil recruitment.
Indication / reason for usePrevention of ocular itching associated with allergic conjunctivitis.
Usual adult dosing1 drop in each eye once daily.
PreservativeBAK 0.005%
Contact lensesRemove lenses before use; reinsert after 10 min.
Common / important adverse effectsEye irritation, burning/stinging, redness, nasopharyngitis.
Contraindications & cautionsHypersensitivity.
Pregnancy / lactationLimited data.
Practice notesOnce-daily dosing aids adherence.
Chair-side reference only. Dosing, contraindications and pregnancy guidance here are not exhaustive. Confirm against the current prescribing information and the patient’s full history before prescribing or advising.

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